Previous studies indicated that chewing gum may relieve stress and depression. There have, however, not
been a significant number of studies on clinical usage of chewing gum. In the present study, 30 patients
with mild to moderate depression were given either medication combined with chewing gum, or medication
only, for 6 weeks. Turkish adaptation of Hamilton Rating Scale for Depression (HAM-D) was used
to measure depression levels. Assessments were conducted by the same physician both before, and after
treatment. The physician who was responsible for the assessment was not aware of the group allocation.
Changes in main HAM-D scores and each item were analyzed by independent samples t test and Chi-
Square test, respectively. Those patients who were administrated chewing gum responded better to
the treatment than patients who took medication only. The most beneficial effect of chewing gum was
observed on the gastrointestinal symptoms, e.g. loss of appetite, and flatulence among others. These
results indicate that chewing gum may not be directly effective on depressed mood; however, it may
reduce the symptoms originating from depression.
Previous studies indicated that chewing gum may relieve stress and depression. There have, however, not
been a significant number of studies on clinical usage of chewing gum. In the present study, 30 patients
with mild to moderate depression were given either medication combined with chewing gum, or medication
only, for 6 weeks. Turkish adaptation of Hamilton Rating Scale for Depression (HAM-D) was used
to measure depression levels. Assessments were conducted by the same physician both before, and after
treatment. The physician who was responsible for the assessment was not aware of the group allocation.
Changes in main HAM-D scores and each item were analyzed by independent samples t test and Chi-
Square test, respectively. Those patients who were administrated chewing gum responded better to
the treatment than patients who took medication only. The most beneficial effect of chewing gum was
observed on the gastrointestinal symptoms, e.g. loss of appetite, and flatulence among others. These
results indicate that chewing gum may not be directly effective on depressed mood; however, it may
reduce the symptoms originating from depression.
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