oesophageal papillomas are known to occur in cattle infected with bovine papillomavirus type 4(BPv-4), and BPV-4 papillomas may undergo malignant progression in cattle that feed on bracken fem. In the south of Italy, where bracken fern is common, examination of 1133 slaughterhouse cattle aged 4-12 years revealed oesophageal lesions(single or multiple peduncuolated proliferations, or mucosal thickening) in 147(13%). These two types of lesion were consistent with exophytic and inverted papilloma, respectively. BPV-4 was detected by polymerase chain reaction(PCR) analysis in >60% of the samples in which oesophageal papilloma was diagnosed histopathologically. Nucleotide sequencing of the PCR amplicons confirmed the presence of BPV-4 in papillomas his is the first report of such infections the in European country other than Britain. a