The absence of the catechol group on apigenin drastically decreased arginase inhibition. Additionally, the docking of compounds showed that the inhibitors interact with amino acids involved in the Mnþ2 Mnþ2 metal bridge formation at the catalytic site.
The absence of thecatechol group on apigenin drastically decreased arginase inhibition. Additionally, the docking of compoundsshowed that the inhibitors interact with amino acids involved in the Mnþ2 Mnþ2 metal bridgeformation at the catalytic site.