Cellulose is one of the most widely used natural substances and has become one of the most important commercial raw materials. The major sources of cellulose are plant fibers (cotton, hemp, flax, and jute are almost all cellulose) and, of course, wood (about 42 percent cellulose). Since cellulose is insoluble in water, it is easily separated from the other constituents of a plant. Cellulose has been used to make paper since the Chinese first invented the process around A.D. 100. Cellulose is separated from wood by a pulping process that grinds woodchips under flowing water. The pulp that remains is then washed, bleached, and poured over a vibrating mesh. When the water finally drains from the pulp, what remains is an interlocking web of fibers that, when dried, pressed, and smoothed, becomes a sheet of paper.