Thus, the NHSS calls for active collaboration and coordination among individuals, families, and communities (including private-sector and all governmental, non-governmental, and academic organizations) to implement strategies to prevent, protect against, respond to, and recover from any type of large-scale incident having health consequences. Achieving national health security also requires better coordination between the health system and the emergency response system; ultimately, these systems need to work together as part of one integrated national health security system. Further, national health security also requires acknowledgment of our Nation’s interdependence with other countries on a global level.