Interestingly, after vaccinated of Nile tilapia with inactivation
S. agalactiae, there was a clear time-dependent expression pattern
of On-CD59 in the skin, brain, head kidney, thymus and spleen, with
quite different kinetic expressions. In the skin, the mRNA expression
level of On-CD59 was up-regulated immediately and reached
its peak at 12 h after immunization. This result might be explained
by complement-mediated mucosal defense mechanisms. Fish live
in aquatic environments, and the mucosal immune system is the
Interestingly, after vaccinated of Nile tilapia with inactivationS. agalactiae, there was a clear time-dependent expression patternof On-CD59 in the skin, brain, head kidney, thymus and spleen, withquite different kinetic expressions. In the skin, the mRNA expressionlevel of On-CD59 was up-regulated immediately and reachedits peak at 12 h after immunization. This result might be explainedby complement-mediated mucosal defense mechanisms. Fish livein aquatic environments, and the mucosal immune system is the
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