7-Eleven is mentioned in the songs "Jesus of Suburbia" and "Homecoming" from Green Day's 2004 album American Idiot, referring to the practice of loitering in front of convenience stores by disaffected youth.
7-Eleven is used in the 2013 movie Escape from Planet Earth
In the Back to the Future trilogy, a man asks Marty McFly where he "learned to shoot like that", Marty tells the man that he learned to shoot whilst playing a Wild Gunman shooting game at 7-Eleven.
7-Eleven is mentioned in the U2 song Stay (Faraway, So Close!) from their 1993 album Zooropa.
7-Eleven is parodied in the games Rebuild, Rebuild 2, and Rebuild: Gangs of Deadsville as 8-Twelve Mart. They don't serve much purpose in the game besides to get food and supplies if any are in the store. However, they can be rebuilt to be something more useful such as an apartment, a bar, or a school.