A different approach to automation is represented by the Zinsser Analytic Lissy-TLC pipetting robot, Fig. 5. The thin-layer plates are positioned in stackable racks, each holding six plates. Samples are spotted at precise locations by the two channel pipettor with one channel used for sample and the other for simultaneous drying with a stream of nitrogen. Up to four pipettors can be used at one time toreduce the time required to apply multiple samples to the layer(s).