Among these lactose derivatives, lactobionic acid (LBA), an aldonic acid named 4-O-β-d-galactopyranosil-d-gluconic acid, can be obtained through the oxidation of lactose. LBA has been largely investigated in the chemical and pharmaceutical sectors. As a pharmaceutical application, it is seen as a promising drug excipient, while the chemical industries are looking for new ways to enhance bio-production and more efficient ways to purify this compound