Our study is the
fi
rst to show that aquatic insects may change behav-
ior after being exposed to dilute concentrations of an antihistamine
(
Fexofenadine
) that is found in aquatic systems receiving wastewater
ef
fl
uent. Further, the high bioconcentration, notably of
Hydroxyzine
,is
very interesting and calls for further studies on mechanisms behind
such bioconcentration and on the implications for both aquatic and
terrestrial consumers that rely on aquatic insects for food. As such, our
results highlight the need to further investigate how aquatic insects
might be affected by antihistamines, other pharmaceuticals, and con-
taminants in general.