10.3. E2 prostaglandins (dinoprostone) [15]
Used as a tampon or vaginal gel, prostaglandins E2 (PGE2) are an effective method of inducing labor (grade A). They can be used to induce labor successfully, regardless of cervical ripeness (grade
A). When cervical conditions are unfavorable, PGE2 can reduce recourse to oxytocin and diminish the doses needed (grade A). The use of PGE2 is associated with a risk of tachysystole that may be
accompanied by abnormal FHR (hyperstimulation syndrome) (grade A).