Gamma-aminobutyric acid (GABA) is a ubiquitous non-protein amino acid which is produced primarily by the แอลฟา-decarboxylation of Glu catalyzed by the enzyme glutamate decarboxylase (GAD. It is well know that GABA functions in animals as a major inhibitory neurotransmitter. GABA is involved in the regulation of cardiovascular functions, as blood pressure and heart rate, and plays a role in the sensations of pain and anxiety. The consumption of GABA-enriched foods such as milk, soybean, tempeh, gabaron tea, red mold rice, and Chlorella has been reported to depress the elevation of systolic blood pressure in spontaneously hypertensive rats ISHRs).