AChE plays an important role in the functioning of the neuromuscular system, preventing continuous muscular contraction. Indeed, it is responsible for the degradation of the neural transmitter acetylcholine to choline in cholinergic synapses and neuromuscular junctions. Inhibition of AChE is followed by acetylcholine accumulation, the post-synaptic membrane remains hyperpolarized, and nervous transmission is interrupted. Therefore, AChE-inhibiting neurotoxic compounds can cause serious dysfunction in aquatic organisms, e.g., behavioural changes, paralysis and death