Some components (mainly
immunoproteins and sodium) cross from plasma into milk
and from milk into the interstitial tissue (especially cytokines)
through this space, inducing an inflammatory response,
most times involving the interlobular connective tissue. The
accumulated milk, the inflammatory response, and the
resulting tissue damage facilitate the establishment of the
infection, usually by Staphylococcus (aureus and albus) and
occasionally by Escherichia coli and Streptococcus (alpha-,
beta- and non-hemolytic), and nipple damage often are the
portal of entry for the bacteria.4
Some components (mainlyimmunoproteins and sodium) cross from plasma into milkand from milk into the interstitial tissue (especially cytokines)through this space, inducing an inflammatory response,most times involving the interlobular connective tissue. Theaccumulated milk, the inflammatory response, and theresulting tissue damage facilitate the establishment of theinfection, usually by Staphylococcus (aureus and albus) andoccasionally by Escherichia coli and Streptococcus (alpha-,beta- and non-hemolytic), and nipple damage often are theportal of entry for the bacteria.4
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