the conceptual model, a number of aspects including waste classes, waste management principles, and waste-to-technology compatibilities were taken into consideration. Based on our conceptual model; we develop a multi-objective mixed integer location/routing model for a national HWMS. This model is capable of determining HW transportation routes, facility locations and capacities. Effects of different HW management strategies and stakeholder priorities can be assessed through scenario development and comparison. To test its effectiveness, the model is applied to Turkey to plan an economical and safe HWMS. Within the scope of the case study, minimum cost, environmental risk, population risk and total risk scenarios are evaluated.