Persistent pain following breast cancer surgery occurs in 25% to 60% of patients (Gartner et al., 2009). This pain problem is associated with mood disturbance, decrements in functional status, and decreases in quality of life (QOL) (Belfer et al., 2013 and Stevens et al., 1995). However, in their recent review of persistent pain following breast cancer treatment, Andersen and Kehlet (2011) identified numerous limitations in the research studies done to date on this significant clinical problem. In addition to inconsistencies in the measurement of pain, only a limited number of studies have assessed for persistent pain in both the breast and shoulder/arm following breast cancer surgery.