This assay, based on coagulating reactions of LAL with endotoxins, is very sensitive and can detect small amounts of endotoxins. In this assay, the endotoxic activity of each bacterial LPS was expressed in terms of its endotoxic equivalence with the LPS of Escherichia coli-type strains. However, several studies have implied that there are big differences between the endotoxic activities of various bacteria determined by LAL assay and their toxic effects on human health ( Hansen et al., 1999 and Dehus et al., 2006)