Given the absence of effect of chamazulene in studies in vitro,
only the EO and -bisabolol were tested in vivo. Gastric lesions
were observed in 2.2%
±
1.8 of EO-treated animals, 5.5%
±
3.2 of -
bisabolol-treated animals, and 93.3%
±
3.9 of controls. In relation
with the larvae isolated from the digestive tract, 23.9% ± 5.6 and
4.4%
±
2.2 were dead in the case of rats treated respectively, with
essential oil and -bisabolol. In the control, all isolated larvae were
alive. In any case we have observed significant changes in the MPO
values (Table 1).