Emetic B. cereus comprise a subgroup of strains, which possess the plasmid-encoded cereulide synthase genes (Ehling-Schulz et al., 2006a). This nonribosomal peptide synthase gene cluster cesHPTABCD, located on a pXO1-like megaplasmid of 200–270 kb, is responsible for the synthesis of the emetic toxin cereulide (Ehling-Schulz et al., 2006a; Dommel et al., 2011). Moreover, the transcription level of ces genes corresponds well with the levels of cereulide produced