Palutena trusts Pit, who is thoroughly loyal and dependable in return. They share a "mutually beneficial" relationship: Pit does the leg-work and Palutena guides him and aids him in battle. By far, her greatest gift, as far as Pit is concerned, is the Power of Flight she bestows upon him.
At first, during Uprising, it can be summarized that she has a tendency to take Pit for granted at times. She very well could have obliterated Pit with her "Palutena Glamblaster/Super Goddess Clobberlaser" when using it to destroy Hewdraw, knowing that he was within the destructive vicinity of the attack, and she thinks nothing of using her "Monster Pheromones" to attract monsters to Pit's location, potentially risking his life as both Hewdraw heads were on the loose. However, during Chapter 22, Palutena clearly states and acknowledges that Pit has made countless sacrifices, both for her and everyone else, revealing that she shares a much deeper bond with him then what anyone knows. In Chapters 20 and 21, she's overjoyed to see Pit who, in return, is relieved to see she's all right. When Pit is unconscious at the end of Chapter 21, Palutena holds him and is very distraught, which highlights just how much she cares for him. Similarly, during Chapter 16, she mentions that she "wouldn't know what she'd do without Pit," causing Pit to remark how sweet it is, whilst the two gods, Hades and Viridi, pretend to be sickened by the display. In response, Palutena simply says, "you wouldn't know anything about loyalty.