modulation of frontocortical and hippocampal acetylcholine levels (5–10 mg/kg Bacopa extract administered to animal models of Alzheimer disease), and modulation of cholinergic neuron densities (Bacopa ethanol extract: 20–80 mg/kg orally ).Such effects of Bacopa have been attributed to the saponins contained within Bacopa,most notably that of bacoside A.1