Ginkgo is intended to stimulate memory[111] and improve circulation. Inhibition of
platelet activating factor receptor leading to hemorrhage is its most common unwanted
effect. The pharmacologically active components are ginkgolides A, B and C, and bilobabides[112]. Case reports have indicated possible risks of spontaneous hemorrhage due
to synergy with several platelet-inhibiting drugs and non-steroidal anti-inflammatory
drugs (NSAIDs). A small study demonstrated that ginkgolides inhibited weal and flare
responses to platelet-activating factor in healthy volunteers, and platelet aggregation in
platelet-rich plasma[113]. A 70-year-old man was reported to suffer from spontaneous