Leukocyte infiltration usually occurs with a delay of 4–6 h after the onset of ischaemia and usually
starts with infiltration of neutrophils.74 Additionally, infiltration of lymphocytes and monocytes/
macrophages also seems to contribute to the post-ischaemic inflammatory reaction.78 Recently, it has
been shown that CD4þ and CD8þ T lymphocytes are critical to focal ischaemic injury.64,76,79,80 In
contrast, regulatory T lymphocytes