In one of the cases of biclonal proliferation (case 1 of Table 5), the blood
picture showed both lymphocytes and lymphoblasts and these two populations
were possibly characterized by different S.Ig markers. Conversely in
the patient affected with a true acute exacerbation and lymphoblastic transformation
of CLL (an extremely rare event), the lymphoblastic population
certainly belonged to the same clone as the lymphocytic population since
both types of cells carried on their surface an 1gM K exhibiting anti-IgG
antibody activity.