AbstractPurpose: This study aimed to examine the effect of a teaching program on knowledge andbehaviors of caregivers to promote nutrition in children with acyanotic congenital heart disease during first year of life.Design: Quasi-experimental research design.Methods: The sample composed of caregivers of children with acyanotic congenital heart disease aged 6-12 months who were waiting for total repair surgery and were treated at a tertiary university hospital. The sample was selected by convenience sampling, and divided into control group and experimental group, with 26 subjects in each group. The experimental group received a teaching program developed by the researcher using Orem’s Educative and Supportive Nursing System as the conceptual framework of this study. Data were collected using the knowledge questionnaire and feeding behaviors questionnaire. Data were analyzed using ANCOVA.Main findings: The experimental group had statistically significant higher mean score of knowledge and behaviours to promote nutrition in children with acyanotic congenital heart disease than those in the control group (F = 5.288, df = 1, p < .05; F = 4.568, df = 1, p < .05; respectively).Conclusion and recommendations: The results suggested that the teaching program is effective in increasing caregivers’ knowledge and behaviors to improve the nutrition of children with acyanotic congenital heart disease during their first year of life. This program may assist these children to receive proper care and better nutrition, maintain better health, without complications, and be prepared for surgery according to treatment plans.Keywords: behaviors, teaching program, caregivers, nutrition promotion, children with acyanotic congenital heart disease