Introduction
25-hydroxyitamin D deficienc is common amongst various
populations worldwide. As per previous studies the prevalence of
vitamin D deficienc varies greatly due to diوٴerences in definitions
used and it ranged from 57% to 74% in in-patient medical population
[1,2]. 70.3% and 67% of an acute inpatient rehabilitation population
and outpatient rehabilitation population respectively were found to
have a serum 25-hydroxyvitamin D of less than 30 ng/ml [3,4].
Vitamin D deficienc has been classically recognized for its role in
bone health, however there is increasing evidence of its role in extraskeletal
health. Investigators of most prospective studies reported
moderate to strong inverse associations between 25(OH) D
concentrations and cardiovascular diseases, serum lipid
concentrations, inflammation, glucose metabolism disorders, weight
gain, infectious diseases, multiple sclerosis, mood disorders, declining
cognitive function, impaired physical functioning, and all-cause
mortality [5].
Нere have been several studies published on the vitamin D status of
rehabilitation patients except one study none of them included
significant number of patients from Asia [6].
We therefore, performed this pilot study with the primary objective
of determining the prevalence of vitamin D screening and association
of vitamin D status with functional outcome in a sampling of patients
in an in-patient rehabilitation unit tertiary care hospital in Singapore.
A secondary objective was to evaluate variables that may influence
vitamin D status.
Introduction25-hydroxyitamin D deficienc is common amongst variouspopulations worldwide. As per previous studies the prevalence ofvitamin D deficienc varies greatly due to diوٴerences in definitionsused and it ranged from 57% to 74% in in-patient medical population[1,2]. 70.3% and 67% of an acute inpatient rehabilitation populationand outpatient rehabilitation population respectively were found tohave a serum 25-hydroxyvitamin D of less than 30 ng/ml [3,4].Vitamin D deficienc has been classically recognized for its role inbone health, however there is increasing evidence of its role in extraskeletalhealth. Investigators of most prospective studies reportedmoderate to strong inverse associations between 25(OH) Dconcentrations and cardiovascular diseases, serum lipidconcentrations, inflammation, glucose metabolism disorders, weightgain, infectious diseases, multiple sclerosis, mood disorders, decliningcognitive function, impaired physical functioning, and all-causemortality [5].Нere have been several studies published on the vitamin D status ofrehabilitation patients except one study none of them includedsignificant number of patients from Asia [6].We therefore, performed this pilot study with the primary objectiveof determining the prevalence of vitamin D screening and associationof vitamin D status with functional outcome in a sampling of patientsin an in-patient rehabilitation unit tertiary care hospital in Singapore.A secondary objective was to evaluate variables that may influence
vitamin D status.
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