The experimental group had significant reductions in stress, anxiety, depression and anger (p < 0.05, Cohen’s d > 50 for all variables).Anxiety and stress were reduced also in the control group, but the effect size was small (p < 0.05, Cohen’s d < 50). Patients in the experimental group were more satisfied in their “need for help” than the control group (p < 0.001, Cohen’s d > 80).Discussion: The integrative intervention has been rated helpful by women with cancer and can be considered useful in lowering negative emotions during the administration of chemotherapy, in particular anger and depression. The limitations of this study and future research directions are discussed