Although paracetamol is believed to have no significant anti-inflammatory activity, it has been reported as effective as aspirin in the treatment of musculoskeletal pain in dogs.[134]
A paracetamol-codeine product (trade name Pardale-V)[135] licensed for use in dogs is available on veterinary prescription in the UK.[135] It should be administered to dogs only on veterinary advice and with extreme caution.[135]
The main effect of toxicity in dogs is liver damage, GI ulceration has been reported.[133][136][137][138] N-acetylcysteine treatment is efficacious in dogs when administered within a 2 hours of paracetamol ingestion