INTRODUCTION
Traumatic brain injury (TBI) remains a significant
cause of death and disability in children worldwide.
In the UK, the incidence of paediatric brain injury
is severe enough to warrant paediatric intensive care
unit (PICU) admission is 5·6 children per 100 000
people per year, and of these, over a half were severe
enough to warrant invasive intracranial pressure (ICP)
monitoring (Parslow et al., 2005). Severe brain injury is