These limitations are potentially offset by strengths of this study. First, the sample size was considerable and as far as we know one of the largest in this field. Further, the present study is the first to investigate specific pregnancy related events compared to general types of events, and interactions between these categories and personality traits as well as childhood trauma. Finally,this study was the first to consider longitudinally assessed change in symptoms of antenatal anxiety or depression in relation to events during pregnancy. This approach makes reverse causality, i. e. events were induced by declining mental health, unlikely. conclusion, the present study shows that during pregnancy. events that are related to pregnancy go with increases in anxiety, whereas levels of depression increase in association with non- pregnancy related events. Compared to pregnancy related events. non-pregnancy related events have more substantial associations with increases in symptoms of anxiety and depression. We found no evidence of modification of these associations by neuroticism. extraversion or childhood trauma. Knowing that antenatal anxiety might have a larger impact on the child's neuromotor development than depression, we think that it is critical to monitor a woman's mental health particularly after the experience of pregnancy related event. Midwives and gynaecologists are ideally suited for this, as they are most likely to be the first contact for pregnant women after experiencing such an event. Our findings may therefore help tailor psychosocial care to the specific risks of a woman and thereby to contribute to the health of mother and child.