Freeze-drying machine applies a technical method by which moisture-bearing samples frozen in advance become dry in the vacuum owing to vaporizing away the moisture. The samples frozen can be well- storage for a long time and returned to their former state once being watered without losing their original biochemical properties. The freeze-drying technology is especially ideal for those bio-products sensitive to antibiotic, vaccines, blood products, enzymes and hormones. This machine is also suitable for sample freezing experiments in labs and small-scale production.