Peptic digestion of bovine hemoglobin at low degree allowed
obtaining antibacterial peptides, against the four bacterial species
tested in this study. It was possible to correlate the antibacterial
activity with the structural properties, the most active being
the shortest one, positively charged, having no or small portion
of hydrophobic residues and having no secondary structure (random
coil). Our work showed also that all of active peptides derived
from 114-145 peptide contained the necessary RYH minimal
antimicrobial sequence, which is the minimal antimicrobial peptidic
sequence from the beta chain of hemoglobin.
In the current context of food safety and food protection by the
way of natural products, using antibacterial peptides from agricultural proteins could be of interest as a preservative for storage and
distribution of food products like meat, and its derived products.