Collagen supplements or formulations may be beneficial in the treatment of osteoarthritis.
In a number of trials,they have been found to provide some degree of pain reduction.
However,in other trials, use of collagen supplements and formulations has not been found to result in any additional benefit.
A 2006 review found that collagen hydrolysate helped to significantly decrease painful symptoms of osteoarthritis while improving joint function.
The supplement was well absorbed,led to collagen accumulation in cartilage, and helped to stimulate specialized cells in the joints called chondrocytes to create extracellular matrix.