Abstract: Xerostomia, the subjective complaint of dry mouth, and hyposalivation remain a
significant burden for many individuals. Diagnosis of xerostomia and salivary gland hypofunction
is dependent upon a careful and detailed history and thorough oral examination. There exist
many options for treatment and symptom management: salivary stimulants, topical agents,
saliva substitutes, and systemic sialogogues. The aim of this review is to investigate the current
state of knowledge on management and treatment of patients affected by xerostomia and/or
hyposalivation.
Keyword: saliva stimulation, dry mouth, saliva substitutes, sialogogues