Note added in proof: After acceptance of this manuscript, Sun
et al. (1992) reported cloning of a human brain cDNA fragment
which contained part of the coding region of a gene homologous
to rat GluR2. The sequence of this fragment was not reported,
thereby precluding its comparison with the putative human homolog
of GluR2 reported here. Hybridization to blots of DNA
isolated from human-hamster somatic cell hybrids localized this
fragment to 4q25-34.3, a region compatible with the localization
of GluR2 to 4q32-33 described in the present report. The
cloning of a full length human brain cDNA homologous to
GluRl was also reported and the amino acid sequence of the
portion corresponding to the exon of GluRl identified here is
identical. Sun et al. (1992) localized the cDNA to human chromosome
5q3 1.3-33.3 by Southern analysis of somatic cell hybrids,
a localization consistent with the present findings.