The present observations reflect that diabetes could be a driving force for the disease process in terms of oxidative stress and inflammation. With the addition of astaxanthin, it is possible to prevent an early liver injury as the result of diabetic complication. Astaxanthin is of interest to many recent researchers because of the anti-inflammatory and anti-atherogenic effects, which stem from its antioxidant role. Besides antioxidant function, other effects specifically receptor activation or interaction with endogenous bioactive factors by astaxanthin must also be considered in future. Astaxanthin can be one of the ingredients in a number of healthy products.