Neuroimaging findings of N. fowleri meningitis show
nonspecific brain edema with evidence of increased
intracranial pressure or cerebral herniation
(91)
. Final
diagnostic confirmation is not achieved until trophozoites
are isolated and identified from cerebrospinal fluid (CSF)
or brain tissue. Lumbar puncture for (CSF) analysis
is the primary diagnostic tool. The CSF mimics that
of acute bacterial meningitis except that Gram stain
is negative. The concentration of erythrocytes in the
CSF may correlate with the degree of necrosis and