Porcine Circovirus type 2 (PCV2) and Mycoplasma hyopneumoniae
are the two most prevalent pathogens encountered in today’s
pig industry. PCV2 was originally identified as the causative agent
of the ‘‘Postweaning Multisystemic Wasting Syndrome’’, but is also
involved in a number of other disease syndromes which have
been collectively named Porcine Circovirus Diseases (PCVD) [1,2].
The most pronounced PCVDs are Porcine Respiratory Disease
Complex (PRDC), Porcine Dermatopathy and Nephropathy
Syndrome, reproductive failure, granulomatous enteritis, congenital
tremors and exudative epidermitis. Subclinical PCV2 infections
are characterized by poor growth performance in apparently
healthy pigs [3–5]. Considering that up to 100% of pigs are seropositive
for PCV2 at the time of slaughter, subclinical PCV2 infection is
currently considered to be the major form of PCVD