The inhibitory effects of 15 on the nitric oxide (NO) production in
lipopolysaccharide (LPS)-activated murine macrophage RAW264.7 cells
were evaluated; all except 3 inhibited NO production at 100 μM. 4 was
the most potent, with an average maximum inhibition and a median inhibitory concentration value of 71.70 ( 1.23% and 65.98 (
0.53 μM, respectively.