The study a problem affected listening comprehension in English of senior. The objective is to study was compare the problems that affect listening comprehension in English between senior students by GPA high and low in the TOEIC test and study the internal and external factors that affected of English majors Kasetsart University Kamphaeng Saen Campus totality 20 people The instrument used for this research was questionnaire was divided into three parts. The first part was about personal information including GPA results and TOEIC. The next part included two sections which were internal factors questions and the external factors. And the last part was other suggestions beside the questionnaire. If the participants would like to give further suggestions, they caused write down on this part. In part one, there were three topics focusing on the factor form the external problems at included teacher teaching, media instruction, Atmosphere were studying and teaching environment. In part two, there were three topics focusing in the factors form the