An 82-year-old female who was routinely followed for bilateral
dry age-related macular degeneration (AMD) was
noted to have corneal thinning in her left eye and referred
to the cornea service for further evaluation. The patient
had a history of hypogammaglobulinemia diagnosed approximately
8.5 years prior to presentation with a documented
history of low immunoglobulin levels, specifically
an IgG of 61 mg/dL, IgA < 16 mg/dL, and IgM< 5 mg/dL.
At that time, she began monthly intravenous immunoglobulin
(IVIG) infusions.