The incubation period of O. tsutsugamushiin humans is
around 10-12d (can vary between 6-21d)[13]. The clinical
manifestations vary in severity from a mild febrile illness to a
severe potentially fatal disease with multi organ dysfunction
syndrome(MODS). The typical systemic features of
infection are well known and include fever, gastrointestinal
disturbances, malaise, cough, myalgia and headache[13]. A
maculopapular rash starting on the trunk and spreading in to
the limbs is seen towards the end of the first week (since the
onset of fever)[13]. Regional lymphadenopathy is commonly
observed.