The results indicate that experimental colonisation of chicks was successful and that the birds showed no
signs of disease even at the highest dose of Campylobacter administered. The phage cocktail was able to reduce
the titre of both C. coli and C. jejuni in faeces by approximately 2 log10 cfu/g when administered by oral gavage
and in feed. This reduction persisted throughout the experimental period and neither pathogen regained their
former numbers. The reduction in Campylobacter titre was achieved earlier (2 days post-phage administration)
when the phage cocktail was incorporated in the birds’ feed. Campylobacter strains resistant to phage infection
were recovered from phage-treated chickens at a frequency of 13%. These resistant phenotypes did not exhibit a
reduced ability to colonize the chicken guts and did not revert to sensitive types.