Different studies were carried on its antibacterial activity upon various microorganisms involving oral and nasopharyngeal infections and especially Streptococcus mutans. An extract of Strebulus asper leaves have demonstrated to possess a selective bactericidal activity towards Streptococcus, especially to S. mutans which has been shown to be strongly linked with dental caries.
The Khoi wood is used throughout South-East Asia as an ingredient mixed with cannabis which reduces the throat irritation associated with inhaling cannabis smoke through a water pipe or bong.