Despite global efforts for reducing the
number of smokers, children are not protected as they are predominantly
exposed at home. Cigarette smoke is a source of both
chemical agents and radiation (polonium). Cotinine, a metabolite
of nicotine, is a commonly used biomarker of exposure to tobacco
smoke. However, cotinine is also an active molecule that can have
impact on human health via several mechanisms. Additionally to
aromatase inhibition (an anti-estrogen activity)