Isoflavonoids from red clover proved to be stable compounds under food processing conditions that could enhance the color and stability of museadine grape anthocyanins. The poor water solubility characteristics of isoflavonoids allowed for successful removal of undesirable components from red clover with hot water without altering the extent of color augmentation, yes when added to wine before or after fermentation sufficient quantities were solubilized into wine to increase phytochemical stability during storage at 20 °C. Although additional research is needed to evaluate the organoleptic and bioactive effects of isoflavonoids in red wine, the isoflavonoid cofactors from red clover were demonstrated to be a viable option for increasing the color stability of muscadine wine and juice.