In this work, a new method of ultrasound-assisted extraction (UAE) of rice lipid was proposed. From the
single-factor experimental design, extraction with hexane resulted in the highest yield compared to
petroleum ether and isopropanol. The amount of extracted rice lipids yields enhanced with increasing
sonication power, temperature and time, respectively. However, excessive sonication power, temperature
and prolonged time would lead to the decrease of rice lipid. A response surface methodology (RSM) was
used to optimize the parameters on UAE based on single factor experiment. Optimum combinations for
lipid extraction yield (77.31%) were hexane, 123W, 42 C and 37 min. The compositions of lipid were
obtained by gas chromatography and mass spectrometry (GC-MS) and no significant differences were
observed between UAE and conventional method.