26
Moreover, there are the investigations with
the antioxidant assay of M. oleifera leaves
extracted with different solvents, they
indicated that the polyphenolic compounds
contained in the extracts were involved in
antioxidant properties. 6, 8 With regard to the
observed results, it is possible that the
antimutagenic activity might be from the
polyphenolic compounds contained by
mechanisms (1) inhibition of the mutagen
penetration into S. typhimurium cells or (2)
neutralization of mutagenic potency prior to
nucleus entering, thus protecting the hot-spot
region of gene from mutation.