Results: 60 women with invasive cervical cancer and 180 healthy controls were interviewed by the investigator.s
Compared with non-users, patients who had ever used or currently used oral contraceptive had an increased
risk of cervical cancer (OR 1.45; 95% CI 0.79-2.64). However, the risk was not statistically significant.
Considering the duration of use, patients who had used oral contraceptives for 3 years or less did not have an
increased risk of cervical cancer (OR 0.78; 95% CI 0.39-1.77). Nevertheless, the odds ratio of oral contraceptive
pill use for more than 3 years was 2.57 (95% CI 1.22-5.49) which was statistically significant.
Conclusion: Long-term use of oral contraceptive might be a cofactor that increases the risk of cervical
carcinoma. Further investigations should be conducted to confirm this risk. However, Pap smear has to be
done routinely in long-term oral pill users