The delivery of a particular substance is influenced by its chemical nature and mechanisms including prolonged release, absorption and surface contact.
A good example of this latter case is sunscreen, whose retention on skin’s surface is desired to reduce both penetration and loss of efficacy.
Studies suggest the cross linked HA gel matrix may impart these effects by either functioning as a reservoir,
slowly releasing active over time; or complexing with the active, to maintain/ retain it on the skin surface.